J-147 has shown benefits in preclinical studies, including reversing cognitive deficits in animal models of Alzheimer’s disease and aging, alleviating the pain of diabetic neuropathy, and exhibiting antidepressant-like and anxiolytic-like effects. It works by promoting neurotrophic factors like BDNF and NGF, and by protecting mitochondrial function. Additional potential benefits include improved outcomes in ischemic stroke and anti-aging effects like reduced blood vessel leakage and improved energy metabolism.
Neuroprotective and cognitive benefits
- Reverses cognitive deficits: J147 can improve memory and cognition in animal models of aging and Alzheimer’s disease.
- Increases neurotrophic factors: It increases the expression of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF), which are important for learning, memory, and brain repair.
- Protects neurons: It shows neuroprotective effects in cell cultures and reduces markers for oxidative stress and inflammation.
- Reduces Alzheimer’s markers: It has been shown to reduce soluble amyloid-beta (Aβ) levels and decrease markers of inflammation in animal models.
Other potential benefits
- Diabetic neuropathy: It alleviates painful symptoms in animal models of diabetic neuropathy.
- Antidepressant and anxiolytic effects: J147 has demonstrated antidepressant and anxiety-reducing activities in animal models.
- Ischemic stroke: It may improve the outcome of ischemic stroke and enhance treatment with tissue plasminogen activator (tPA).
- Anti-aging effects: It shows anti-aging effects in animal models, such as preventing blood vessel leakage in the brain and improving energy metabolism in cells.
Mechanism of action
- Mitochondrial function: J147 targets a protein in mitochondria (ATP synthase), which helps maintain cellular energy production and protects against cell death.
- Metabolic effects: It can decrease blood plasma free fatty acid levels by activating a pathway in the liver that supports energy production.
To summarize: J-147 has demonstrated to reduce plaque buildup in the brain, reduce free fatty acids in the blood, aids in repair of fatty liver, reduces atherosclerosis, and improves production of serotonin.
This is some of the benefits of J-147.
Amount 60 capsules
Directions:
1 capsule 2 times a day preferably on a empty stomach, however some of our testers took capsule after eating and had similar results.
Ingredients:
J-147 10mg
Proprietary Amino Acid Complex
rice flour
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